167869-21-8
267.3
C16H13NO3
DMSO
-20°C
Cell-permeable, potent and specific inhibitor of MAP Kinase (MEK or MAPK/ERK). By selectively blocking the activity of MEK, it also inhibits the phosphorylation and activation of MAP kinase.Transcriptional activation of the IL31 gene by NFAT and STAT6.Differential Role of PKC Isoforms in GnRH and Phorbol 12-Myristate 13-Acetate Activation of Extracellular Signal-Regulated Kinase and Jun N-Terminal Kinase.Glycogen Synthase Kinase-3 Plays a Central Role in Mediating Glucocorticoid-Induced Apoptosis.Effect of Oncostatin M on Uridine Diphosphate-5'-Glucuronosyltransferase 1A1 through Cross Talk with Constitutive Androstane Receptor.Loss of E-Cadherinmediated CellCell Contacts Activates a Novel Mechanism for Up-Regulation of the Proto-Oncogene.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
