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Price$ 47.25
  • SKU: P-2394-1MG
  • Pack Size: 1 MG
Quantity
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+

3-[4-(4-morpholinyl)pyrido[3’,2’:4,5]furo[3,2-d]pyrimidin-2-yl]-phenol

371935-74-9

348.4

C19H16N4O3

DMF, DMSO

-20°C


PI-103 is a cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110), and mTOR. The ICvalues are 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110, mTORC1, PI3-KC2, p110, mTORC2, p110, and p110, respectively. Inhibits growth of human tumor xenografts in mice in vivo.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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