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Price$ 402.50
  • SKU: G-2347-25MG
  • Pack Size: 25 MG
Quantity
-
+

5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine

870483-87-7

366.4

C20H22N4O3

DMF, DMSO

-20°C


GW 2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse macrophages in vitro.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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