2-Cyano-N-(2,5-dibromophenyl)-3-hyd¬roxy-2-butenamide
62004-35-7
360.0
C11H8Br2N2O2
DMSO, Ethanol
-20°C
LFM-A13 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits recombinant BTK with an IC50 = 2.5 μM and has no activity at other protein kinases (including JAK1, JAK3, HCK, EGFR kinase and insulin receptor kinase) at concentrations up to 300 μM.
Research or further manufacturing use only, not for food or drug use.