PF 2341066
877399-52-5
450.3
C21H22Cl2FN5O
DMF, DMSO, Ethanol, DMF:PBS (pH 7.2)(1:1)
-20°C
(R)-Crizotinib is a specific, ATP-competitive, small-molecule inhibitor of the receptor tyrosine kinases (RTKs) c-Met and anaplastic lymphoma kinase (ALK). Iinhibits tyrosine phosphorylation of activated ALK at nanomolar concentrations. Inhibits the growth and survival of cell lines dependent upon c-Met or ALK enzymatic activity.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
