5-Aza-2’-deoxycitidine; 5Aza-CdR; 2’-deoxy-5-azacytidine
2353-33-5
228.21
C8H12N4O4
Water
-20°C
Decitabine is an analogue of the nucleoside 2-deoxycytidine that acts as an epigenetic modifier. It is believed to exert its antineoplastic effects after phosphorylation and direct incorporation into DNA and inhibition of DNA methyltransferase, causing hypomethylation of DNA and cellular differentiation or apoptosis.
DNA hypomethylation is achieved at concentrations below those required to significantly inhibit DNA synthesis, which may promote restoration of function to genes associated with control of cellular differentiation and proliferation.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
