N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formylbutyl]-L-leucinamide
133407-86-0
461.6
C25H39N3O5
DMF, DMSO, Ethanol
-20°C
(S)-MG115 is a potent, reversible inhibitor of the 20S proteasome (Ki = 21 nM) and 26S proteasome (Ki = 35 nM). Cells treated with 54 μM N-CBZ-Leu-Leu-Norvalinal showed complete block of the G1/S and metaphase transitions and delayed passage through S-phase. Induces apoptosis in Rat-1 and PC12 cells.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
