Immunosuppressive agent Mycophenolic acid (MPA) inhibits inosine monophosphate dehydrogenase. It selectively inhibits lymphocyte proliferation by blocking the enzyme, inosine monophosphate dehydrogenase, part of in the guanosine monophosphate pathway. It has been tested extensively in renal transplant patients and has been shown to be effective in reducing the incidence of acute graft rejection.
• Used in the de novo synthesis of purine nucleotides
• Used in clinical settings as a chemotherapeutic or immunosuppressant agent
• Used for transfected animal cells expressing the E. coli gene for xanthine-guanine phosphoribosyl transferase
|Handling||Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.|
|UN #'S||UN 3077|