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Bleomycin Sulfate, Streptomyces verticillus, (Mixture of Bleomycin A2, B2, and B4)

Price$ 460.25
  • SKU: B-1269-250MG
  • Pack Size: 250MG
Quantity
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Bleomycin Sulfate, Streptomyces verticillus, (Mixture of Bleomycin A2, B2, and B4)

Blenoxane; Blexane; Bleomycin sulphate

9041-93-4

1400

Water

2-8°C


Bleomycin Sulfate is an anti-neoplastic antibiotic from Streptomyces verticillus. It binds to DNA and can inhibit DNA synthesis and causes scission of DNA. Able to cleave DNA and also RNA, but at less and more selective a degree. Also reported to induce and regulate apoptosis in a variety of cells, and inhibit tumor angiogenesis.

 

Produces double and single stranded DNA breaks. Inhibitis intracellular DNA replication. DNA alkylating agent.

 

 



Research or further manufacturing use only, not for food or drug use.
  • Appearance: White to off-white amorphous powder
  • Identification (IR & Sulfate): Conforms to Standard
  • Content of Bleomycin A2: 55 - 70 %
  • Content of Bleomycin B2: 25 - 32 %
  • Content of Bleomycin B4: ≤ 1 %
  • Purity (HPLC) A2+B2: ≥ 90
  • Copper: ≤ 0.1 %
  • Loss on Drying: ≤ 6.0 %
  • Potency (USP Bleomycin Units): 1.5 - 2.0 U/mg
  • pH: 4.5 - 6.0
  • Bacterial Endotoxins: ≤ 10 EU/U
  • Solubility (20 mg/ml in Water): Freely Soluble in H2O

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