May be dissolved in DMSO
Thalidomide binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A inhibiting ligase activity. Inhibits TNFα synthesis and FGF-induced angiogenesis. Cell permeable.
Caution: Teratogenic. Pregnant women should avoid using this compound.
Not for human therapeutic use or for medicinal purposes. For research applications only.
Research or further manufacturing use only, not for food or drug use.