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Thalidomide, 500 MG

Price$ 385.94
  • SKU: T-1020-500MG
  • Pack Size: 500 MG
Quantity
-
+

50-35-1

258.2

C13H10N2O4

May be dissolved in DMSO

Room Temperature


Description

Thalidomide binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A inhibiting ligase activity. Inhibits TNFα synthesis and FGF-induced angiogenesis. Cell permeable.

Caution: Teratogenic. Pregnant women should avoid using this compound.

 

References

• Identification of a Primary Target of Thalidomide Teratogenicity

• Inhibition of tumor necrosis factor-alpha by thalidomide in magnesium deficiency

• Thalidomide is an inhibitor of angiogenesis

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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