Oncodazole; R 17934; [5-(2-Thienylcarbonyl)-1Hbenzimidazol -2-yl]-carbamic acid methyl ester; Methyl N- (5-thenoyl-2-benzimidazolyl)carbamate; Methyl [5-(2- thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
31430-18-9
301.3
C14H11N3O3S
DMSO, Dimethyl Formamide
2-8°C
Nocodazole is a synthetic and reversible microtubule inhibitor. It inhibits microtubule polymerization and makes the arrests cells at the G2/M phase. It binds to beta-tubulin and suppresses mitotic spindles
Due to its anti-mitotic properties, it is used to induce apoptosis and for production of mitotic mammalian cells. Arrested cell cycles by the drug can return to normal cell cycles when it is removed.
Nocodazole has been reported certain concentrations of nocodazole increase p53 and p53-DNA binding and accumulate p21 mRNA in NIH-3T3 fibroblasts.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
