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Price$ 66.75
  • SKU: P-1101-1MG
  • Pack Size: 1 MG
Quantity
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Phosphoramidon sodium salt ; N-(αRhamno­pyranosyl­oxy­hydroxy­phosphinyl)-Leu-Trp disodium salt; N-(α-Rhamno­pyranosyl­phos­phono)-Lleucyl-L-tryptophan disodium salt

119942-99-3

587.47

C23H32N3O10P • 2Na

Water, DMSO, Methanol

-20°C


Phosphoramidon inhibits neutral endopeptidase 24.11 (NEP, neprilysin; EC 3.4.24.11) (Ki=2nM), a cell surface zinc metalloprotease which cleaves bioactive peptides such as bradykinin, neurotensin, and enkephalin. Also inhibits neprilysin 2 (Ki~2nM). Potent inhibitor of endothelin-converting enzyme (ECE) (IC50=0.68 μM).

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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