119942-99-3
587.47
C23H32N3O10P • 2Na
Water, DMSO, Methanol
-20°C
Phosphoramidon inhibits neutral endopeptidase 24.11 (NEP, neprilysin; EC 3.4.24.11) (Ki=2nM), a cell surface zinc metalloprotease which cleaves bioactive peptides such as bradykinin, neurotensin, and enkephalin. Also inhibits neprilysin 2 (Ki~2nM). Potent inhibitor of endothelin-converting enzyme (ECE) (IC50=0.68 μM).
0.1 lbs
Research or further manufacturing use only, not for food or drug use.