Soluble in EtOH (10 mg/mL) and DMSO (20 mg/mL)
An irreversible, highly selective cysteine protease inhibitor and cell permeable analog of E-64D. Specifically E-64D is an irreversible cathepsin L and B inhibitor.
E-64d has played an imporant role in studies of the Ebola virus (EBOV). E-64d has been shown to lead to the accumulation of CTFs and AICD with no change ingamma and beta secretase activities. Additionally, utilizing E-64d has shown results in accumulation of autophagic bodies inside vacuoles in Arabidopsis root cells.
Not for human therapeutic use or for medicinal purposes. For research applications only.
Research or further manufacturing use only, not for food or drug use.