(2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3- methybutane ethyl ester EST; Aloxistatin; Loxistatin
E-64d is an irreversible cathepsin L and B inhibitor.
E-64d has played an imporant role in studies of the Ebola virus (EBOV). E-64d has been shown to lead to the accumulation of CTFs and AICD with no change ingamma and beta secretase activities. Additionally, utilizing E-64d has shown results in accumulation of autophagic bodies inside vacuoles in Arabidopsis root cells.
Research or further manufacturing use only, not for food or drug use.