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Elastatinal, 5 MG

Price$ 84.45
  • SKU: E-2044-5MG
  • Pack Size: 5 MG
Quantity
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(2S)-2-[(4S)-2-Amino-1,4,5,6-tetrahydro4-pyrimidinyl]-N- [[[(1S)-1- carboxy-3-methylbutyl]amino]carbonyl]glycylN1-[(1S)-1-methyl -2-ox

51798-45-9

512.56

C21H36N8O7

Water

-20°C


Description:

Elastatinal is a tetrapeptide derivative with an aldehyde group which is essential for inhibitory activity such as pancreatic elastase. It is a much stronger inhibitor of elastase from pancreas than from leucocytes because it’s isolated from Actinomycetes.
 

Elastatinal is a highly specific inhibitor of elastase-like serine proteases. Elastatinal can also be used as an inhibitor for thermitase, a thermostable serine protease from Thermoactinomyces vulgaris, and for macroglobulin-protease complexes.
 

Elastatinal inhibits the proteolytic activity of poliovirus and rhinovirus 2A proteinases in vitro. Additionally, it has no effect on DNA repair and UV-induced sister chromatid exchanges, and inhibits the cleavages found at Ala-Ala bonds in peptides that represent the capsid/nucleocapsid site. Elastatinal is an irreversible inhibitor of neutrophil and rat microglia elastase.
 

Applications:

  • Used as a microbial product inhibitor for elastase
  • Ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro
  • Ability to reduce rate of degradation of endostain
  • Used to effectively inhibit phenylmethylsulfonyl fluoride

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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