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Leucinostatin A, 2.5 MG

Price$ 1,254.00
  • SKU: L-2539-2.5MG
  • Pack Size: 2.5 MG
Quantity
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+

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Total price: $ 1,685.50

This item: Leucinostatin A, 2.5 MG $ 1,254.00

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P168

76600-38-9

1218.6

C62H111N11O13

DMF, DMSO, Ethanol, Methanol

-20°C


Leucinostatin A is the major component of atypical nonapeptide complex and a fungal metabolite isolated from Paecilomyces lilacinus. Leucinostatins show broad bioactivity against Gram-positive bacteria, fungi, plants and tumor cell lines. It inhibits respiration by uncoupling oxidative phosphorylation and is potentiated by inhibitors such as venturicidin and oligomycin.

 

It is believed that leucinostatin A suppresses the activation of T lymphocytes. It acts as a weak ionophore facilitating the transport of mono- and divalent cations through the plasma membrane of T lymphocytes and through artificial membranes.
 

It has been reported that it has an activity as an insulin-like growth factor I regulator, an ionophore, inhibitor of cell surface expression of viral glycoproteins and its anti-trypanosomal activity.


Applications

• Antibiotic

• Ionophore

• Immunosuppressive agent

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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